Oncologist Recommendation For Immediate Treatment

  1. Biopsy
    1. To confirm receptor status and provide tissue for further testing re clinical trial eligibility
  2. Consider radiotherapy to rib lesion for pain relief (best to do early rather than need to interrupt systemic treatment)
    1. Dr Marita Morgia’s team to arrange appointment
  3. Clinical trial
    1. JAVELIN PARP Medley trial (avelumab plus talazoparib)– Prof Richard Kefford at Macquarie University Hospital
    2. b. Other options include:
      1. Keytruda (pembrolizumab) – self-funded
      2. Another clinical trial
  4. ARCS- Multi tumour (anetumab ravtansine in mesothelin expressing advanced solid tumours) – Prof Richard Kefford at Macquarie University Hospital
  5. Xgeva (denosumab) to treat and protect bones (to be discussed)

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