Oncologist Recommendation For Immediate Treatment I Louise DeCelis

Biopsy
1. To confirm receptor status and provide tissue for further testing re clinical trial eligibility
Consider radiotherapy to rib lesion for pain relief (best to do early rather than need to interrupt systemic treatment)
1. Dr Marita Morgia’s team to arrange appointment
Clinical trial
1. JAVELIN PARP Medley trial (avelumab plus talazoparib)– Prof Richard Kefford at Macquarie University Hospital
2. b. Other options include:
  1. Keytruda (pembrolizumab) – self-funded
  2. Another clinical trial
ARCS- Multi tumour (anetumab ravtansine in mesothelin expressing advanced solid tumours) – Prof Richard Kefford at Macquarie University Hospital
Xgeva (denosumab) to treat and protect bones (to be discussed)